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Young coffee leaflets were fed with [U- 14 C]adenine of [Me- 14 C]methionine, and the incorporation of radioactivity into purines (purine bases, nucleosides, nucleotides, nucleic acids) and purine alkaloids (PA) (7-methylxanthine, theobromine, caffeine) was determined after 4 and 24 hr. Labelling of PA was considerable after 4 hr (i.e. about 38 or 71% of the recovered radioactivity...