Search results for: Alex Z. Fu

Items from 1 to 20 out of 35 results

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Mood outcomes of a behavioral treatment for urinary incontinence in prostate cancer survivors

Amy Y. Zhang, Stephen Ganocy, Alex Z. Fu, Denise Kresevic, more

Supportive Care in Cancer > 2019 > 27 > 12 > 4461-4467

Purpose This study aimed to assess whether prostate cancer survivors who received a behavioral intervention to urinary incontinence had experienced a significant mood improvement. Methods One hundred fifty-three prostate cancer survivors with persistent incontinence were included in this secondary data analysis. They were randomly assigned to usual care or interventions that provided pelvic floor...

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Health-related quality of life among rural men and women with hypertension: assessment by the EQ-5D-5L in Jiangsu, China

Zhuoru Liang, Tiantian Zhang, Tengfei Lin, Lishun Liu, more

Quality of Life Research > 2019 > 28 > 8 > 2069-2080

Purpose Hypertension is a major global public health problem, including rural China. However, studies examining health-related quality of life (HRQoL) for patients with hypertension have been mostly conducted in urban populations. This study aimed to use the EuroQol five-dimensional-five-level (EQ-5D-5L) and its recently developed Chinese value set to analyze HRQoL and its influencing factors among...

article

Rates of myocardial infarction and stroke in patients initiating treatment with SGLT2‐inhibitors versus other glucose‐lowering agents in real‐world clinical practice: Results from the CVD‐REAL study

Mikhail Kosiborod, Kåre I. Birkeland, Matthew A. Cavender, Alex Z. Fu, more

Diabetes, Obesity and Metabolism > 20 > 8 > 1983 - 1987

The multinational, observational CVD‐REAL study recently showed that initiation of sodium‐glucose co‐transporter‐2 inhibitors (SGLT‐2i) was associated with significantly lower rates of death and heart failure vs other glucose‐lowering drugs (oGLDs). This sub‐analysis of the CVD‐REAL study sought to determine the association between initiation of SGLT‐2i vs oGLDs and rates of myocardial infarction...

article

Hospitalization for Heart Failure and Death in New Users of SGLT-2 Inhibitors in Patients With and Without Cardiovascular Disease—CVD Real Study

Matthew A. Cavender, Anna Norhammar, Kare I. Birkeland, Marit Eika Jorgensen, more

Canadian Journal of Diabetes > 2017 > 41 > 5(S) > S51-S52

article

Mortality and Androgen Deprivation Therapy as Salvage Treatment for Biochemical Recurrence after Primary Therapy for Clinically Localized Prostate Cancer

Alex Z. Fu, Huei-Ting Tsai, Reina Haque, Marianne Ulcickas Yood, more

The Journal of Urology > 2017 > 197 > 6 > 1448-1454

Androgen deprivation therapy is often used as salvage treatment in men with rising prostate specific antigen after initial radical prostatectomy or radiotherapy for clinically localized prostate cancer. Given the lack of evidence from general practice, we examined the association of salvage androgen deprivation therapy with mortality in an observational cohort study.From 3 managed care organizations...

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Risks of Serious Toxicities from Intermittent versus Continuous Androgen Deprivation Therapy for Advanced Prostate Cancer: A Population Based Study

Huei-Ting Tsai, Ruth M. Pfeiffer, George K. Philips, Ana Barac, more

The Journal of Urology > 2017 > 197 > 5 > 1251-1257

Randomized trials have shown that intermittent androgen deprivation therapy for patients with advanced prostate cancer may improve sexual and physical functioning compared to continuous androgen deprivation therapy without compromising survival. To our knowledge it is unknown whether intermittent androgen deprivation therapy alters the risk of serious toxicities associated with continuous androgen...

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Is a behavioral treatment for urinary incontinence beneficial to prostate cancer survivors as a follow-up care?

Amy Y. Zhang, Alex Z. Fu, Shirley Moore, Hui Zhu, more

Journal of Cancer Survivorship > 2017 > 11 > 1 > 24-31

Purpose The American Cancer Society (ACS) recommends a follow-up care plan for urinary incontinence of prostate cancer survivors that includes pelvic floor muscle exercise (PFME). We examined potential impacts and access barriers of this recommendation with consideration of patients who normally do not seek such care. Methods We compared 267 participants of a clinical trial that tested a PFME-based...

article

Cost‐effectiveness of a behavioral intervention for persistent urinary incontinence in prostate cancer patients

Amy Y. Zhang, Alex Z. Fu

Psycho‐Oncology > 25 > 4 > 421 - 427

ObjectiveThe aim of this study was to evaluate the cost‐effectiveness of a behavioral intervention for urinary incontinence of prostate cancer patients. Study subjects were either participating in or eligible but declined (i.e., nonparticipating) the active intervention study. MethodsThe intervention‐participating subjects were randomized into three groups, including two intervention groups (support...

article

Patient preference and decision-making for initiating metastatic colorectal cancer medical treatment

Alex Z. Fu, Kristi D. Graves, Roxanne E. Jensen, John L. Marshall, more

Journal of Cancer Research and Clinical Oncology > 2016 > 142 > 3 > 699-706

Purpose Some medical treatment for metastatic colorectal cancer (CRC) may have marginal survival benefit, but cause toxicities. The purpose of this study is to determine metastatic CRC patients’ tradeoffs in making a decision to undergo new medical treatment. Methods We conducted a survey of patients with a diagnosis of advanced CRC who were currently receiving or completed one chemotherapy regimen...

article

Cardiovascular toxicity after antiangiogenic therapy in persons older than 65 years with advanced renal cell carcinoma

Sekwon Jang, Chaoyi Zheng, Huei‐Ting Tsai, Alex Z. Fu, more

Cancer > 122 > 1 > 124 - 130

BACKGROUNDSorafenib and sunitinib are oral vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKIs) approved in 2005 and 2006, respectively, for the treatment of patients with renal cell carcinoma (RCC). A population‐based, observational cohort study of the cardiovascular risk of VEGFR TKI therapy in elderly RCC patients was conducted. METHODSUsing the Surveillance, Epidemiology,...

article

Effects of Patient Centered Interventions on Persistent Urinary Incontinence after Prostate Cancer Treatment: A Randomized, Controlled Trial

Amy Y. Zhang, Donald R. Bodner, Alex Z. Fu, Douglas D. Gunzler, more

The Journal of Urology > 2015 > 194 > 6 > 1675-1681

We examined whether an intervention combining pelvic floor muscle exercise and symptom self-management would improve urinary continence and quality of life in patients with prostate cancer.In a randomized, controlled, longitudinal clinical trial 279 patients with prostate cancer with persistent urinary incontinence were randomized to 1 of 3 groups, including biofeedback pelvic floor muscle exercise...

article

Risk characterization for urinary tract infections in subjects with newly diagnosed type 2 diabetes

Alex Z. Fu, Kristy Iglay, Ying Qiu, Samuel Engel, more

Journal of Diabetes and Its Complications > 2014 > 28 > 6 > 805-810

To evaluate the risk of urinary tract infections (UTI) in subjects with newly diagnosed type 2 diabetes mellitus (T2DM).Subjects aged ≥18years and diagnosed with T2DM between 1/1/10 and 12/31/10 were identified using the MarketScan® databases, which are representative of the commercially insured US population and those with both Medicare and supplemental coverage. The index date was the first T2DM...

article

Disease burden of urinary tract infections among type 2 diabetes mellitus patients in the U.S.

Shengsheng Yu, Alex Z. Fu, Ying Qiu, Samuel S. Engel, more

Journal of Diabetes and Its Complications > 2014 > 28 > 5 > 621-626

Type 2 diabetes is a reported risk factor for more frequent and severe urinary tract infections (UTI). We sought to quantify the annual healthcare cost burden of UTI in type 2 diabetic patients.Adult patients diagnosed with type 2 diabetes were identified in MarketScan administrative claims data. UTI occurrence and costs were assessed during a 1-year period. We examined UTI-related visit and antibiotic...

article

Feasibility of an Online Mindfulness Program for Stress Management—A Randomized, Controlled Trial

Thomas J. Morledge, Didier Allexandre, Emily Fox, Alex Z. Fu, more

Annals of Behavioral Medicine > 2013 > 46 > 2 > 137-148

Background Chronic stress affects many Americans. Stress management programs may be prohibitively expensive or have limited access. Purpose This study aims to determine feasibility of an 8-week Internet-based stress management program (ISM) based on mindfulness principles in reducing stress in a 12-week, parallel, randomized, controlled trial. Methods Participants were randomly allocated to ISM,...

article

CLOPIDOGREL IS UNDERUSED IN PATIENTS WITH ACUTE CORONARY SYNDROME

Qiaoyi Zhang, Alex Z. Fu, Michael Davies, Edmond Chen

Journal of the American College of Cardiology > 2012 > 59 > 13(S) > E499

article

READMISSION RATES AMONG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND TREATED WITH ASPIRIN OR DUAL ANTIPLATELET THERAPY DURING HOSPITALIZATION

Qiaoyi Zhang, Alex Z. Fu, Michael Davies, Edmond Chen

Journal of the American College of Cardiology > 2012 > 59 > 13(S) > E1889

article

Initial Sulfonylurea Use and Subsequent Insulin Therapy in Older Subjects with Type 2 Diabetes Mellitus

Alex Z. Fu, Ying Qiu, Michael J. Davies, Samuel S. Engel

Diabetes Therapy > 2012 > 3 > 1 > 1-9

Background In type 2 diabetes mellitus (T2DM), progressive loss of beta cell function over time requires treatment intensification and eventually initiation of insulin for many patients. Relative to metformin, a greater rate of decline in beta cell function over time has been observed with sulfonylurea treatment. The present study examined the association between initial monotherapy with metformin...

article

A time-motion economic analysis of postoperative nausea and vomiting in ambulatory surgery

Ivan Parra-Sanchez, Rania Abdallah, Jing You, Alex Z. Fu, more

Canadian Journal of Anesthesia/Journal canadien d'anesthésie > 2012 > 59 > 4 > 366-375

Background One-third of surgical outpatients experience postoperative nausea and vomiting (PONV) during their hospital stay or post-discharge nausea and vomiting (PDNV) after hospitalization. We determined the incremental costs of PONV/PDNV in ambulatory patients with this time-and-motion study. Methods In 100 ambulatory surgery patients, we evaluated the incidence of PONV, time staff spent with...

article

Race and intensity of post-remission therapy in acute myeloid leukemia

Anna K. Brady, Alex Z. Fu, Marc Earl, Matt Kalaycio, more

Leukemia Research > 2011 > 35 > 3 > 346-350

In many cancers, including AML, blacks have poorer overall survival. We investigated whether differences in post-remission therapy (PRT) were a contributing factor.We compared PRT cycle number and intensity and time to PRT in blacks and whites, among 460 patients with newly diagnosed AML.Blacks and whites had PRT of equal cycle intensity and number, but black patients experienced a significant delay...

article

Marginal differences in health-related quality of life of diabetic patients with and without macrovascular comorbid conditions in the United States

Alex Z. Fu, Ying Qiu, Larry Radican, Nan Luo

Quality of Life Research > 2011 > 20 > 6 > 825-832

Purpose To examine and quantify, at the US national level, the marginal differences in health-related quality of life (HRQoL) of diabetic patients with and without macrovascular comorbid conditions (MaVCC). Methods Using the pooled Medical Expenditure Panel Survey (MEPS) 2001 and 2003 data, a nationally representative community-dwelling adult sample (age ≥ 18) was included in the study. HRQoL measures...

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Search results for: Alex Z. Fu

Mood outcomes of a behavioral treatment for urinary incontinence in prostate cancer survivors

Health-related quality of life among rural men and women with hypertension: assessment by the EQ-5D-5L in Jiangsu, China

Rates of myocardial infarction and stroke in patients initiating treatment with SGLT2‐inhibitors versus other glucose‐lowering agents in real‐world clinical practice: Results from the CVD‐REAL study

Hospitalization for Heart Failure and Death in New Users of SGLT-2 Inhibitors in Patients With and Without Cardiovascular Disease—CVD Real Study

Mortality and Androgen Deprivation Therapy as Salvage Treatment for Biochemical Recurrence after Primary Therapy for Clinically Localized Prostate Cancer

Risks of Serious Toxicities from Intermittent versus Continuous Androgen Deprivation Therapy for Advanced Prostate Cancer: A Population Based Study

Is a behavioral treatment for urinary incontinence beneficial to prostate cancer survivors as a follow-up care?

Cost‐effectiveness of a behavioral intervention for persistent urinary incontinence in prostate cancer patients

Patient preference and decision-making for initiating metastatic colorectal cancer medical treatment

Cardiovascular toxicity after antiangiogenic therapy in persons older than 65 years with advanced renal cell carcinoma

Effects of Patient Centered Interventions on Persistent Urinary Incontinence after Prostate Cancer Treatment: A Randomized, Controlled Trial

Risk characterization for urinary tract infections in subjects with newly diagnosed type 2 diabetes

Disease burden of urinary tract infections among type 2 diabetes mellitus patients in the U.S.

Feasibility of an Online Mindfulness Program for Stress Management—A Randomized, Controlled Trial

CLOPIDOGREL IS UNDERUSED IN PATIENTS WITH ACUTE CORONARY SYNDROME

READMISSION RATES AMONG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND TREATED WITH ASPIRIN OR DUAL ANTIPLATELET THERAPY DURING HOSPITALIZATION

Initial Sulfonylurea Use and Subsequent Insulin Therapy in Older Subjects with Type 2 Diabetes Mellitus

A time-motion economic analysis of postoperative nausea and vomiting in ambulatory surgery

Race and intensity of post-remission therapy in acute myeloid leukemia

Marginal differences in health-related quality of life of diabetic patients with and without macrovascular comorbid conditions in the United States

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