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We have examined specific genes whose expression is altered during apoptosis induced by prostaglandin (PG)A 2 and Δ 12 -PGJ 2 in human hepatocellular carcinoma Hep3B cells. Using mRNA differential display, we have identified two genes: one is specifically up-regulated and encodes for human Sox-4 (Sry-HMG box gene) and the other is significantly down-regulated and is the...