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A straightforward procedure ensuring the anchoring of bisphosphonate moiety onto aromatic amines is described. The procedure yields aminoaryl 1,1-bisphosphonates known to display multiple biological activities. The described methodology has also been applied to the synthesis of ligands whose uranyl-binding properties have been studied.
A new procedure for synthesis of 14 C-labeled tentoxin [ 14 C-MePhe[(Z)Δ] 3 -tentoxin], with a high specific activity, is described. Binding experiments with CF 1 or CF 1 - isolated from spinach chloroplast have been carried out using equilibrium dialysis technique. The results show the presence of two classes of binding sites. The association...
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