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The last major advance in the treatment of glioblastoma multiforme (GBM) was the introduction of temozolomide in 1999. Treatment with temozolomide following surgical debulking extends survival rate compared to radiotherapy and debulking alone. However, virtually all glioblastoma patients experience disease progression within 7 to 10months. Although many salvage treatments, including bevacizumab, rechallenge...
Guillain-Barré syndrome (GBS) is an acute peripheral neuropathy caused by an autoimmune response against myelin of peripheral nerves. GBS has been reported after surgery, in general, and after spinal surgery, in particular. In most cases, GBS developed 1–3 weeks after surgery.Report of 2 cases of GBS after elective spine surgery that developed in the immediate postoperative period.Within 1 and 3 hours...
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