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Twenty triterpene saponins (1–20) have been isolated from different parts of Chenopodium quinoa (flowers, fruits, seed coats, and seeds) and their structures have been elucidated by analysis of chemical and spectroscopic data including 1D- and 2D-NMR. Four compounds (1–4) were identified: 3β-[(O-β-d-glucopyranosyl-(1→3)-α-l-arabinopyranosyl)oxy]-23-oxo-olean-12-en-28-oic acid β-d-glucopyranoside (1),...
Silybin or silymarin extract has been used to treat liver diseases, and has now been entered into clinical trials for cancer treatment. Here, we compared antioxidant and anticancer activities between silybin and its oxidized form 2,3-dehydrosilybin (DHS). With IC 50 at three-fold lower concentrations than silybin, DHS inhibited reactive oxygen species generation in glucose–glucose oxidase...
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