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Le test Access OV Monitor (Beckman-Coulter) est une technique immunoenzymatique chimiluminescente, utilisee pour le dosage du CA 125. L'evaluation analytique a permis d'apprecier la limite de detection (0,1 U/ml), la precision totale s'echelonnant de 2,6 a 5,2 %. La linearite apres dilution a ete validee sur dix serums de concentrations elevees en CA 125 (taux de recouvrement de 97 a 112 %). L'intervalle...
A candidate gene (HFE) has been described for hereditary hemochromatosis on chromosome 6. The study of well-defined atypical hemochromatosis families using genetic markers may increase our understanding of the sensitivity and the specificity of genotyping in hemochromatosis. One hundred and thirteen Canadian families with genetic hemochromatosis were surveyed to find atypical families as possible...
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