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The effects of transforming growth factor α (TGFα) on low and high density cultures of fetal (embryonic day 17) rat medial septal cells were investigated and in some instances, compared to those of epidermal growth factor (EGF). In high density cultures, TGFα induces a significant increase in the number of astroglia and microglia. While the effects of TGFα on the astroglia are more pronounced when...