Search results for: Gary W. Donaldson

Items from 1 to 20 out of 34 results

article

Impact of an automated, remote monitoring and coaching intervention in reducing hospice cancer family caregiving burden: A multisite randomized controlled trial

Kathi H. Mooney, Lorinda A. Coombs, Meagan S. Whisenant, Christina M. Wilson, more

Cancer > 130 > 7 > 1171 - 1182

Background Care for those with life‐limiting cancer heavily involves family caregivers who may experience significant physical and emotional burden. The purpose of this study was to test the impact of Symptom Care at Home (SCH), an automated digital family caregiver coaching intervention, during home hospice, when compared to usual hospice care (UC) on the primary outcome of overall caregiver burden...

article

Fear of older adult falling questionnaire for caregivers (FOAFQ‐CG): Evidence from content validity and item‐response theory graded‐response modelling

Rumei Yang, Gary W. Donaldson, Linda S. Edelman, Kristin G. Cloyes, more

Journal of Advanced Nursing > 76 > 10 > 2768 - 2780

Aims (1) Determine the content validity of the Fear of Older Adult Falling Questionnaire‐Caregivers using a panel of gerontological experts and a target sample of family caregivers (Stage 1) and (2) Examine the response patterns of the Fear of Older Adult Falling Questionnaire‐Caregivers and compare it with older adult version of Fear of Falling Questionnaire Revised using graded‐response modelling...

article

Patient-reported outcomes for patients with metastatic castration-resistant prostate cancer receiving docetaxel and Atrasentan versus docetaxel and placebo in a randomized phase III clinical trial (SWOG S0421)

Joseph M. Unger, Katherine Griffin, Gary W. Donaldson, Karen M. Baranowski, more

Journal of Patient-Reported Outcomes > 2018 > 2 > 1 > 1-10

Background SWOG S0421 was a large randomized trial comparing docetaxel/prednisone plus placebo (DPP) to docetaxel/prednisone plus atrasentan over 12 cycles for patients with metastatic castration-resistant prostate cancer (mCRPC). The current report presents the PRO results for this trial, an important secondary endpoint. Methods The trial specified two primary PRO endpoints. Palliation of worst...

article

Caregiver, patient, and nurse visit communication patterns in cancer home hospice

Maija Reblin, Margaret F. Clayton, Jiayun Xu, Jennifer M. Hulett, more

Psycho‐Oncology > 26 > 12 > 2285 - 2293

Objective Few studies have examined the triadic communication between patients, spouse caregivers, and nurses in the home hospice setting. Thus, little is known about the types of communication patterns that unfold. The goals of the study were to, first, identify common patterns of communication in nurse‐patient‐caregiver home hospice visits and, second, to identify nurse, caregiver‐patient dyad,...

article

The challenge of measuring intra-individual change in fatigue during cancer treatment

Carol M. Moinpour, Gary W. Donaldson, Kimberly M. Davis, Arnold L. Potosky, more

Quality of Life Research > 2017 > 26 > 2 > 259-271

Purpose To evaluate how well three different patient-reported outcomes (PROs) measure individual change. Methods Two hundred and fourteen patients (from two sites) initiating first or new chemotherapy for any stage of breast or gastrointestinal cancer participated. The 13-item FACIT Fatigue scale, a 7-item PROMIS^® Fatigue Short Form (PROMIS 7a), and the PROMIS^® Fatigue computer adaptive test (CAT)...

article

Gene Expression Factor Analysis to Differentiate Pathways Linked to Fibromyalgia, Chronic Fatigue Syndrome, and Depression in a Diverse Patient Sample

Eli Iacob, Alan R. Light, Gary W. Donaldson, Akiko Okifuji, more

Arthritis Care & Research > 68 > 1 > 132 - 140

ObjectiveTo determine if independent candidate genes can be grouped into meaningful biologic factors, and whether these factors are associated with the diagnosis of chronic fatigue syndrome (CFS) and fibromyalgia syndrome (FMS), while controlling for comorbid depression, sex, and age. MethodsWe included leukocyte messenger RNA gene expression from a total of 261 individuals, including healthy controls...

article

Breast Cancer Risk Perceptions among Relatives of Women with Uninformative Negative BRCA1/2 Test Results: The Moderating Effect of the Amount of Shared Information

Deborah O. Himes, Margaret F. Clayton, Gary W. Donaldson, Lee Ellington, more

Journal of Genetic Counseling > 2016 > 25 > 2 > 258-269

The most common result of BRCA1/2 mutation testing when performed in a family without a previously identified mutation is an uninformative negative test result. Women in these families may have an increased risk for breast cancer because of mutations in non-BRCA breast cancer predisposition genes, including moderate- or low-risk genes, or shared environmental factors. Genetic counselors often encourage...

article

Reduction in salivary α-amylase levels following a mind–body intervention in cancer survivors—An exploratory study

David L. Lipschitz, Renee Kuhn, Anita Y. Kinney, Gary W. Donaldson, more

Psychoneuroendocrinology > 2013 > 38 > 9 > 1521-1531

The main aim of this exploratory study was to assess whether salivary α-amylase (sAA) and salivary cortisol levels would be positively modulated by sleep-focused mind–body interventions in female and male cancer survivors.We conducted a randomized controlled trial in which 57 cancer survivors with self-reported sleep disturbance received either a Sleep Hygiene Education (SHE; n=18) control, or one...

article

Confirmatory Factor Analysis of the Pain Care Quality Surveys (PainCQ^©)

Marjorie A. Pett, Susan L. Beck, Jia‐Wen Guo, Gail L. Towsley, more

Health Services Research > 48 > 3 > 1018 - 1038

ObjectiveTo examine the reliability and validity and to decrease the battery of items in the Pain Care Quality (PainCQ^©) Surveys. Data Sources/Study SettingPatient‐reported data were collected prospectively from 337 hospitalized adult patients with pain on medical/surgical oncology units in four hospitals in three states. Study DesignThis methodological study used a cross‐sectional survey design...

article

Investigating efficacy of two brief mind–body intervention programs for managing sleep disturbance in cancer survivors: a pilot randomized controlled trial

Yoshio Nakamura, David L. Lipschitz, Renee Kuhn, Anita Y. Kinney, more

Journal of Cancer Survivorship > 2013 > 7 > 2 > 165-182

Purpose After completing treatment, cancer survivors may suffer from a multitude of physical and mental health impairments, resulting in compromised quality of life. This exploratory study investigated whether two mind–body interventions, i.e., Mind–Body Bridging (MBB) and Mindfulness Meditation (MM), could improve posttreatment cancer survivors’ self-reported sleep disturbance and comorbid symptoms,...

article

Resolution of Acute Pain Following Discharge From the Emergency Department: The Acute Pain Trajectory

C. Richard Chapman, David Fosnocht, Gary W. Donaldson

Journal of Pain > 2012 > 13 > 3 > 235-241

We demonstrate and evaluate a method for modeling acute pain resolution in individual patients over 6 days following an emergency department visit for an acutely painful condition. Five hundred and thirteen patients presenting with acutely painful conditions provided 11-point numerical ratings of pain intensity at discharge from an emergency department and daily thereafter for a total of 6 days. Latent...

article

Investigating dose-dependent effects of placebo analgesia: A psychophysiological approach

Yoshio Nakamura, Gary W. Donaldson, Renee Kuhn, David H. Bradshaw, more

Pain > 2012 > 153 > 1 > 227-237

Investigating dose-dependent effects of placebo analgesia (PA) in laboratory subjects undergoing pain testing, we evaluated 2 hypotheses: (1) greater expectancy for relief produces greater PA, and (2) cued expectancy for relief triggered by a predictive cue leads to more enhanced analgesia than does passive expectancy (no predictive cue). We used conditioning procedures in which 84 subjects experienced...

article

Evaluating health-related quality-of-life therapeutic effectiveness in a clinical trial with extensive nonignorable missing data and heterogeneous response: results from a phase III randomized trial of gemcitabine plus paclitaxel versus paclitaxel monotherapy in patients with metastatic breast cancer

Carol M. Moinpour, Gary W. Donaldson, Astra M. Liepa, Allen S. Melemed, more

Quality of Life Research > 2012 > 21 > 5 > 765-775

Purpose This manuscript presents health-related quality of life (HRQL) results from a phase III trial of gemcitabine-paclitaxel (GT) versus paclitaxel (T) in metastatic breast cancer patients. Methods Patients completed the Rotterdam Symptom Checklist (RSCL) and Brief Pain Inventory (BPI) at baseline and at the end of each cycle. Sensitivity analyses for six longitudinal pattern mixture models (PMMs)...

article

Postoperative Pain Trajectories in Chronic Pain Patients Undergoing Surgery: The Effects of Chronic Opioid Pharmacotherapy on Acute Pain

C. Richard Chapman, Jennifer Davis, Gary W. Donaldson, Justin Naylor, more

Journal of Pain > 2011 > 12 > 12 > 1240-1246

For 2 weeks following surgery, 55 patients with preexisting chronic pain (CP) reported daily postoperative pain with movement and at rest. Of these, 30 CP patients used opioid pharmacotherapy for CP management and 25 did not. We modeled pain resolution in each patient using a linear fit so that each patient yielded 2 scores for each pain rating: 1) an intercept, or initial level of pain, immediately...

article

Individual Differences in the Effects of Music Engagement on Responses to Painful Stimulation

David H. Bradshaw, Gary W. Donaldson, Robert C. Jacobson, Yoshio Nakamura, more

Journal of Pain > 2011 > 12 > 12 > 1262-1273

Engaged attention, including music listening, has shown mixed results when used as a method for reducing pain. Applying the framework of constructivism, we extend the concept of engagement beyond attention/distraction to include all cognitive and emotional/motivational processes that may be recruited in order to construct an alternative experience to pain and thus reduce pain. Using a music-listening...

article

Improving Individual Measurement of Postoperative Pain: The Pain Trajectory

C. Richard Chapman, Gary W. Donaldson, Jennifer J. Davis, David H. Bradshaw

Journal of Pain > 2011 > 12 > 2 > 257-262

The purpose of this study was to demonstrate a method for increasing the precision and information yield of postoperative pain assessment. We recorded pain intensity ratings over 6 days after surgery in 502 elective surgery patients and examined individual pain trajectories. A linear fit of an individual patient's scores defines a trajectory with two features: (1) the intercept or initial pain intensity;...

article

Sequential Analyses of Daily Symptoms in Women With Fibromyalgia Syndrome

Akiko Okifuji, David H. Bradshaw, Gary W. Donaldson, Dennis C. Turk

Journal of Pain > 2011 > 12 > 1 > 84-93

Fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain disorder characterized by generalized pain, chronic fatigue, sleep disturbance, and a range of other symptoms having no definitive pathology. Consequently, patient evaluations rely on self-report. Ecological Momentary Assessment (EMA) allows frequent real-time collection of self-report measures, removing recall bias and increasing external...

article

Relationship Between Fibromyalgia and Obesity in Pain, Function, Mood, and Sleep

Akiko Okifuji, Gary W. Donaldson, Lynn Barck, Perry G. Fine

Journal of Pain > 2010 > 11 > 12 > 1329-1337

Fibromyalgia syndrome (FMS) is a prevalent and disabling chronic pain disorder. Past research suggests that obesity is a common comorbidity and may be related to the severity of FMS. The main objective of the present study was to evaluate the relationships between FMS and obesity in the multiple FMS-related domains: hyperalgesia, symptoms, physical abilities, and sleep. A total of 215 FMS patients...

article

Opioid Pharmacotherapy for Chronic Non-Cancer Pain in the United States: A Research Guideline for Developing an Evidence-Base

C. Richard Chapman, David L. Lipschitz, Martin S. Angst, Roger Chou, more

Journal of Pain > 2010 > 11 > 9 > 807-829

This document reports the consensus of an interdisciplinary panel of research and clinical experts charged with reviewing the use of opioids for chronic noncancer pain (CNCP) and formulating guidelines for future research. Prescribing opioids for chronic noncancer pain has recently escalated in the United States. Contrasting with increasing opioid use are: 1) The lack of evidence supporting long-term...

article

Chemotherapeutic impact on pain and global health-related quality of life in hormone-refractory prostate cancer: Dynamically Modified Outcomes (DYNAMO) analysis of a randomized controlled trial

Carol M. Moinpour, Gary W. Donaldson, Yoshio Nakamura

Quality of Life Research > 2009 > 18 > 2 > 147-155

Purpose This paper applies the Dynamically Modified Outcomes (DYNAMO) model to a clinical trial of two chemotherapeutic regimens on global health-related quality of life (GHRQL) in hormone-refractory prostate cancer. Methods DYNAMO identifies the causal influences operating in a clinical trial and their mediation, moderation, and modulation by uncontrolled variables. The Southwest Oncology Group...

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INFONA - science communication portal

Search results for: Gary W. Donaldson

Impact of an automated, remote monitoring and coaching intervention in reducing hospice cancer family caregiving burden: A multisite randomized controlled trial

Fear of older adult falling questionnaire for caregivers (FOAFQ‐CG): Evidence from content validity and item‐response theory graded‐response modelling

Patient-reported outcomes for patients with metastatic castration-resistant prostate cancer receiving docetaxel and Atrasentan versus docetaxel and placebo in a randomized phase III clinical trial (SWOG S0421)

Caregiver, patient, and nurse visit communication patterns in cancer home hospice

The challenge of measuring intra-individual change in fatigue during cancer treatment

Gene Expression Factor Analysis to Differentiate Pathways Linked to Fibromyalgia, Chronic Fatigue Syndrome, and Depression in a Diverse Patient Sample

Breast Cancer Risk Perceptions among Relatives of Women with Uninformative Negative BRCA1/2 Test Results: The Moderating Effect of the Amount of Shared Information

Reduction in salivary α-amylase levels following a mind–body intervention in cancer survivors—An exploratory study

Confirmatory Factor Analysis of the Pain Care Quality Surveys (PainCQ^©)

Investigating efficacy of two brief mind–body intervention programs for managing sleep disturbance in cancer survivors: a pilot randomized controlled trial

Resolution of Acute Pain Following Discharge From the Emergency Department: The Acute Pain Trajectory

Investigating dose-dependent effects of placebo analgesia: A psychophysiological approach

Postoperative Pain Trajectories in Chronic Pain Patients Undergoing Surgery: The Effects of Chronic Opioid Pharmacotherapy on Acute Pain

Individual Differences in the Effects of Music Engagement on Responses to Painful Stimulation

Improving Individual Measurement of Postoperative Pain: The Pain Trajectory

Sequential Analyses of Daily Symptoms in Women With Fibromyalgia Syndrome

Relationship Between Fibromyalgia and Obesity in Pain, Function, Mood, and Sleep

Opioid Pharmacotherapy for Chronic Non-Cancer Pain in the United States: A Research Guideline for Developing an Evidence-Base

Chemotherapeutic impact on pain and global health-related quality of life in hormone-refractory prostate cancer: Dynamically Modified Outcomes (DYNAMO) analysis of a randomized controlled trial

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