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Erlotinib induced skin toxicity has been associated with clinical benefit in several tumour types. This phase II study evaluated the efficacy of erlotinib, dose escalated to rash, in patients with advanced pancreatic cancer previously treated with gemcitabine.Erlotinib was given at an initial dose of 150mg/day, and the dose was escalated by 50mg every 2weeks (to a maximum of 300mg/day) until >grade...