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The high molecular weight isoforms (a and b) of microtubule-associate protein 2 (MAP2a,b) are widely believed to be specific markers for neuronal somata and dendrites. We analyzed and quantified MAP2a,b stained dendrites of the cerebellar molecular layer using a novel approach that segmented and 3D reconstructed them, and the results have been compared with those obtained by other methods, including...
The dentate nucleus is the largest single structure linking the cerebellum to the rest of the brain. The peculiar shape and large size of the human dentate nucleus have sparked a number of theories about the role of the cerebellum in human evolution. Some of the proposed ideas could be explored by comparative studies of humans and apes, but comparative studies are hindered because of the complex three...
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