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Soluble RAGE (sRAGE), endogenous secretory RAGE (esRAGE) and oxidative stress played important roles in the pathogenesis of diabetes and its complications. The changes in sRAGE and esRAGE during pre-diabetes were indefinite.Patients were divided into NGT, pre-diabetes (pre-DM), and newly diagnosed diabetes mellitus (DM) groups according to blood glucose levels. The levels of sRAGE, esRAGE, 8-isoprostaglandin...