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Sarcopenia has been defined as low muscle mass and physical performance, and recognition of its importance in clinical practice is growing. Declines in muscle mitochondrial function with age have been described although less is known about the role of mitochondrial dysfunction in sarcopenia. The aim of this study was to investigate whether respiratory chain deficiency is associated with muscle mass...
Background Sarcopenia, the loss of muscle mass and strength, is associated adversely with disability, morbidity and mortality. disability, morbidity and mortality. Epidemiological findings suggest influences operating across the life course may be important. course may be important. Our aim was to ascertain the feasibility and acceptability of obtaining muscle tissue from healthy older people in order...
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