The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Many isoprenylated proteins are known to participate in signal transduction, but not all have been identified. Using an in vitro prenylation screen, two human cDNAs (PTPcaaxi and PTPcaax2) homologous to the rat PRL-1 and human OV-1 protein tyrosine phosphatase genes were identified. PTPcaaxi and PTPcaax2 were farnesylated in vitro by mammalian farnesyl:protein transferase, and epitope-tagged PTPcaax2...