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Kinesins are microtubule (MT)‐based motors involved in various cellular functions including intracellular transport of vesicles and organelles, and dynamics of chromosomes during cell division. The fission yeast Schizosaccharomyces pombe expresses nine kinesin‐like proteins (klps). Klp8 is one of them and has not been characterized yet though it has been reported to localize at the division site....
Mitotic cyclin‐dependent kinase (CDK) is activated by Cdc25 phosphatase through dephosphorylation at the Wee1‐mediated phosphorylation site. In Saccharomyces cerevisiae, regulation of Mih1 (Cdc25 homologue) remains unclear because inactivation/degradation of Swe1 (Wee1 homologue) is the main trigger for G2/M transition. By deleting all mitotic cyclins except Clb2, a strain was created where Mih1 became...
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