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Hippocampal slices of newborn rats were exposed to either heat-inactivated Streptococcus pneumoniae R6 (hiR6) equivalent to 10 6 and 10 8 CFU/ml, lipoteichoic acid (LTA) (0.3 μg/ml and 30 μg/ml), peptidoglycans (PG) (0.3, 30, 50 and 100 μg/ml), pneumococcal DNA (pDNA) (0.3 and 30 μg/ml) or medium only (control). Cell injury was examined by Nissl staining, Annexin V and NeuN immunohistochemistry,...