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Critical design attributes of angioplasty balloons include the following: tear resistance, high burst pressures, controlled compliance, and high fatigue. Balloons must have tear resistance and high burst pressures because a calcified stenosis can be hard and nominal pressures of up to 16atm can be used to expand the balloon. The inflated balloon diameter must be a function of the inflation pressure,...
Sirolimus‐containing poly(lactide‐co‐glycolide) (PLGA) films were prepared by solution casting and removing the residual solvent, 1,4‐dioxane, by liquid and supercritical carbon dioxide (CO2) extraction. The effect of lactide:glycolide ratio, stereochemistry of PLGA, and extraction condition (i.e., temperature and pressure) on the polymer and drug morphologies was studied using wide‐angle X‐ray scattering...
Konjac glucomannan (KGM) exhibited liquid crystalline (LC) behaviour in aqueous solutions above 7% (w/w) concentrations as was determined by polarized optical microscopy and circular dichroism. The rheological properties of the concentrated LC solutions of KGM exhibited pseudoplastic behaviour. The fibrous extrudates retained a significant degree of flow-induced orientation as was determined by...
Continuous fibers from blends of cellulose acetate butyrate (CAB) with lignin (L) were spun from liquid crystalline solution. Morphological investigations suggest that CAB and L form blends with considerable phase mixing. The porosity of the surface structure of CAB/L fibres increased with increasing L content. The mechanical properties of the L-containing fibres increased with phase mixing of...
Poly(lactic acid) (PLA) was melt blended with poly(vinyl acetate) (PVA) using a single-screw extruder. The extruded films obtained were characterized for miscibility, physical properties, degradation and surface morphology. Differential scanning calorimetry showed that all the as-extruded films were amorphous, and that the blends were compatible as only one glass transition temperature was observed...
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