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Helicobacter pylorivacuolating cytotoxin (VacA) induces gastric epithelial necrosis. ItsC-terminal domain is hypothesized to be responsible for extracellular translocation of the mature cytotoxin. In this study, genetic-structural properties of VacAC-terminal domain and the level of cytotoxin secretion were investigated.Sau3AI-HaeIII restriction fragment length polymorphism (RFLP) analysis of the...