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Wnt signaling plays critical roles in development of various organs and pathogenesis of many diseases, and augmented Wnt signaling has recently been implicated in mammalian aging and aging-related phenotypes. We here report that complement C1q activates canonical Wnt signaling and promotes aging-associated decline in tissue regeneration. Serum C1q concentration is increased with aging, and Wnt signaling...
The fluorescence spectra of intermolecular and intramolecular toluene-amine and toluene-diamine systems were measured in THF. The fluorescence spectrum of toluene-N,N,N',N'-tetramethyl-1,4-butanediamine (TMBD) mixtures was decomposed into four component bands with the shortest-wavelength band (band A) assigned to the excited toluene. Of the remaining bands, the short-wavelength (band B), the middle-wavelength...
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