Search results for: Hans Van Rostenberghe

Items from 1 to 9 out of 9 results

article

Randomised controlled trial: Shoulder–umbilicus length versus body weight measurement for optimal endotracheal tube depth estimation in ventilated infants

Adam Al‐Anas bin Mat Ali, Ariffin Nasir, Noraida Ramli, Nor R Ibrahim, more

Journal of Paediatrics and Child Health > 56 > 5 > 704 - 709

Aim The optimal placement of the endotracheal tube (ETT) in ventilated infants is essential, but birthweight may be not the best parameter to predict it. The aim of this study was a direct comparison of shoulder–umbilical length (experimental group) versus birthweight (control group) as predictor of optimal ETT placement in Malaysian ventilated infants. Methods All infants requiring ventilation...

article

High resolution melting analysis of the NR1I3 genetic variants: Is there an association with neonatal hyperbilirubinemia?

Tian Pei Cheung, Hans Van Rostenberghe, Rosliza Ismail, Noor Namirah Nawawi, more

Gene > 2015 > 573 > 2 > 198-204

Constitutive androstane receptor (CAR) encoded by the nuclear receptor subfamily 1, group I, member 3 (NR1I3) gene regulates the elimination of bilirubin through activating the components of the bilirubin clearance pathway. Hence, NR1I3 genetic variants may affect bilirubin metabolism and result in neonatal hyperbilirubinemia. Thus far, research which investigates the association between NR1I3 variants...

article

Randomised controlled trial of single phototherapy with reflecting curtains versus double phototherapy in term newborns with hyperbilirubinaemia

Intan Juliana Abd Hamid, Mohd Igbal@Iqbal M Iyen, Nor Rosidah Ibrahim, Noorizan Abd Majid, more

Journal of Paediatrics and Child Health > 49 > 5 > 375 - 379

AimThe use of reflecting curtains with single phototherapy has not yet been directly compared with double phototherapy (DP). The objective of this study is to compare the efficacy of single phototherapy with reflecting curtains (SPRC) and DP in treating neonatal jaundice. MethodsThis randomised controlled trial involved 160 term newborns with severe neonatal jaundice in the first 2 weeks of life...

article

Comparison of antimicrobial resistance in neonatal and adult intensive care units in a tertiary teaching hospital

Noorzaitun Ariffin, Habsah Hasan, Noraida Ramli, Nor Rosidah Ibrahim, more

AJIC: American Journal of Infection Control > 2012 > 40 > 6 > 572-575

Intrahospital variations in antimicrobial profiles may be related to many factors. This study compared causative agents of nosocomial bloodstream infections between a neonatal intensive care unit (NICU) that adopted a ward-tailored antibiotic policy and adult intensive care units (ICUs). Data on organisms from blood cultures obtained from the respective wards between 2005 and 2009 were analyzed. Compared...

article

Non‐attendance to the paediatric clinics in a Malaysian tertiary hospital: A sizeable problem and identification of an efficacious intervention

Mohammad Tamim Jamil, Nik Zainal Abidin Nik Ismail, Azman Bin Zulkifli, Noorizan Abdul Majid, more

Journal of Paediatrics and Child Health > 47 > 6 > 346 - 349

Aim: To determine the rate, causes and risk factors of non‐attendance to the paediatric clinic in a tertiary hospital in Malaysia and to determine the efficacy of one telephone call to confirm a new appointment. Methods: For all non‐attending patients, during a 2‐month period, a pro forma was filled up based on patients' records. During a phone call, additional questions were asked, and a new appointment...

article

Discovering potential, transforming life

Hans Van Rostenberghe, Muhamad Saiful Bahri Yusoff, Tan Ying Jie, Suliana Shamsuddin, more

Medical Education > 44 > 5 > 504 - 505

article

First isolation of Burkholderia tropica from a neonatal patient successfully treated with imipenem

Zakuan Zainy Deris, Hans Van Rostenberghe, Hassan Habsah, Ramli Noraida, more

International Journal of Infectious Diseases > 2010 > 14 > 1 > e73-e74

We report the first case of a human Burkholderia tropica infection. The patient was a premature neonate who had necrotizing enterocolitis with bowel perforation requiring surgical intervention. The stoma care and difficulties in feeding were a chronic problem. At the age of almost 4 months he developed septicemia due to B. tropica. Three consecutive blood cultures grew this organism. The organism...

article

Evaluation of mutation effects on UGT1A1 activity toward 17β-estradiol using liquid chromatography–tandem mass spectrometry

Keiko Wada, Atsuko Takeuchi, Kayoko Saiki, Retno Sutomo, more

Journal of Chromatography B > 2006 > 838 > 1 > 9-14

Mutations in the gene encoding UDP-glucuronosyltransferase 1A1 (UGT1A1) may reduce the glucuronidation of estradiol, bilirubin, etc. In the present study, we used a liquid chromatography–tandem mass spectrometry (LC/MS/MS) method to assay the activities of recombinant mutated UGT1A1 toward 17β-estradiol (E2), by determining its glucuronide (E2G) content. Direct evidence for glucuronide formation was...

article

High prevalence of Southeast Asian ovalocytosis in Malays with distal renal tubular acidosis

Narazah Mohd Yusoff, Hans Van Rostenberghe, Taku Shirakawa, Kaoru Nishiyama, more

Journal of Human Genetics > 2003 > 48 > 12 > 650-653

Southeast Asian ovalocytosis (SAO) is a red blood cell abnormality common in malaria-endemic regions and caused by a 27 nt deletion of the band 3 protein gene. Since band 3 protein, also known as anion exchanger 1, is expressed in renal distal tubules, the incidence of SAO was examined in distal renal tubular acidosis (dRTA) in Malays in Kelantan, Malaysia. Twenty-two patients with dRTA and 50 healthy...

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