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Odkrycie molekuł alergenowych zrewolucjonizowało diagnostykę alergii, która dotąd opierała się wyłącznie na wywiadzie, analizie objawów występujących u pacjenta oraz oznaczeniach swoistych immunoglobulin E (sIgE) wobec ekstraktów alergenowych in vivo i in vitro. Testy oparte na molekułach pozwalają lepiej zrozumieć alergię oraz przynoszą wiele korzyści pacjentom. Diagnostyka alergii dzięki diagnostyce...
Apelin is considered an important gut regulatory peptide with potential physiological roles in gastrointestinal cytoprotection and regulation of food intake and drinking behavior. The aim of this study was to determine the effects of intraperitoneal or intragastric apelin administration on gastric and intestinal epithelial apoptosis, mitosis and DNA repair enzyme 8-oxoguanine (OGG 1/2) expression...
In the presented studies p53 protein expression was evaluated in samples of gastric carcinoma originating from 32 selected adult patients (with documented diagnosis of adenocarcinoma of the stomach and without the presence of Helicobacter pylori infection). Among the patients 14 individuals carried EBV-positive gastric carcinoma (group 1) while the 18 remaining patients carried EBV-negative gastric...
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