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The effect of a salt-based diet on the coronary responsiveness in aged hypertensive rats (SHR) still is unclear. We investigated the effects of high salt intake on the relaxation properties of coronary arteries of aged SHRs. Male SHR (32week-old) received drinking water (SHR) or 1% NaCl solution (SHR-Salt) for 8weeks. Isolated coronary segments were subjected to concentration–response curves to acetylcholine...