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BackgroundIncreased mucus production is a critical factor impairing lung function in patients suffering from bronchial asthma, the most common chronic inflammatory lung disease worldwide.
ObjectiveThis study aimed at investigating whether goblet cell (GC) metaplasia and mucus production are differentially regulated in proximal and distal airways.
MethodsFemale Balb/c mice were sensitized to ovalbumin...
Aqueous solutions of the triblock copolymer poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) EO13PO30EO13 (Pluronic L64) were investigated over a wide concentration range (20–100%, (w/w) polymer) in the micellar, liquid crystalline and reverse micellar phases, using electron spin resonance (ESR) spectroscopy of spin probes. A series of amphiphilic nitroxide spin probes based on...
We present a study of sulfonated polyimide block ionomer membranes (SPIs) in the dry state, and swollen by water, methanol, ethanol, and dioxane. The ionomers are based on a naphthalenic dianhydride and differ in the ionic exchange capacity and the type of diamine in the hydrophobic block. The ionomers were studied by electron spin resonance (ESR) spectroscopy of the paramagnetic transition metal...
The local parameters (hydration, order, viscosity) in different aggregates (mi-celle, hexagonal and lamellar liquid crystals) in the phase diagram of poly(oxyethylene) [5]-dodecylether (C12E5) in water have been measured by EPR with two series of spin probes: x-DSA, (x == 5, 7, 10, 12 and 16) and CAT n (11. == 4, 8, 11 and 16). A rather complete map of hydration ([H20]/[Ea]) along the PEa chains has...
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