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P53 is tumor suppressor gene that plays important roles in regulating cell cycles in human including cell cycles arrest(inhibit cellular growth) and cell death[l]. It can be triggered by damaged DNA, ionizing agents or oxidative stress via transcription process". After p53 IS triggered, it is called "p53 transcription factor". The function of p53 transcription factor is related to programmed...
The relationship between the in vitro susceptibility of Plasmodium falciparum isolates to the quinoline antimalarials chloroquine (CQ), mefloquine (MQ), and quinine (QN), and pfcrt and pfmdr1 gene polymorphisms were investigated. Field isolates (110 samples) were collected from various endemic areas of Thailand throughout 2002–2004. The pfcrt 76T allele was identified in 109 isolates (99.1%) while...
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