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Neural Stem Cells: Development and Transplantation provides comprehensive, critical and insightful reviews by leading experts in this exciting field of research. This volume will provide the latest data on neural stem cell properties and their therapeutic applications. This volume will be particularly useful for students, basic scientists, and clinicians in the academic or industrial sectors who have...
Growth factor-dependent proliferation of neuronal progenitors is an essential stage in CNS development. Although several of these growth factors have been identified, high levels of neuregulin 1 (NRG1) mRNA and protein expression in the CNS during the time of neuronal progenitor expansion suggest NRG1 growth factors may also play a key role in their proliferation. No previous studies have examined...
Mollusk-derived growth factor (MDGF), the first growth factor to be characterized in Aplysia, was purified and characterized and has both adenosine deaminase activity and stimulates cell proliferation in vitro. MDGF is structurally related to a new subfamily of adenosine deaminase-related growth factors that require enzymatic activity to stimulate cell proliferation, a unique property of known growth...
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