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Kinesin and kinesin-related proteins are microtubule-dependent motor proteins that transport organelles. We have cloned and sequenced a full-length 9924bp mouse cDNA for a new kinesin of the UNC-104/KIF1 subfamily. Northern blot analysis of mouse RNAs detected high levels of a 10kb mRNA in brain and eye, but lower levels in other tissues. Human RNA dot-blot analysis detected this mRNA in all tissues...
The chickWDR1gene is expressed at higher levels in the chick basilar papilla after acoustic overstimulation. The 3.3-kbWDR1cDNA encodes a novel 67-kDa protein containing nine WD40 repeats, motifs that mediate protein–protein interactions. The predicted WDR1 protein has high sequence identity to WD40-repeat proteins in budding yeast (Saccharomyces cerevisiae), two slime molds (Dictyostelium discoideumandPhysarum...
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