The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The growth characteristics in vitro of interleukin 2 (IL 2)-dependent human CD4 + αβ-T cell receptor-positive helper T cell clones (TCC) were studied in relation to alterations in surface phenotype, cytokine responsiveness, and susceptibility to activation-induced cell death (AICD). TCC derived from peripheral blood T cells had finite lifespans averaging 33 population doublings (PD) with...
A condition of hyporesponsiveness can be induced in certain mature human αβ (TCR2) cells relatively easily by their stimulation in the absence of costimulatory signals (signal 1 alone). This state of 'anergy' has been implicated in tolerance to self and transplanted organs as well as tumors and may represent an important regulatory component or immune responsiveness. Little is known about whether...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.