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Stem cells have a host of applications in regenerative medicine and basic research. However, clinical translation hinges on the availability of effective stem cell expansion. Stem cell expansion has been limited due to the use of xenogenic factors in the culture system, batch-to-batch variation, and processes that do not readily lend themselves to scale-up. Synthetic substrates represent attractive...
The ability to reversibly modulate macroscopic surface properties is an important requirement for numerous biomedical applications, such as cell culture, tissue engineering, biosensors, biofouling and microfluidics. While dynamic remodeling of materials and interfaces is a widely observed phenomenon in nature, examples of synthetic systems that can be switched on-demand are scarce. Recently, numerous...
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