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Depuis sa découverte en 1948, le méthotrexate (MTX) a vu son champ d'application s'étendre et c'est en cherchant à vaincre les résistances à ce médicament que le concept de MTX à haute dose a été proposé. Afin de prescrire une posologie optimale du médicament, pour obtenir le meilleur effet thérapeutique avec une toxicité moindre, on a réalisé, parallèlement aux études de pharmacocinétique, un ≪ sauvetage...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.