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Optical imaging of intrinsic signals and conventional electrophysiological methods were used to investigate the correlation between the evoked activity in mouse visual cortex and core body temperature. The results show that hypothermia (25–36 °C) decreases the intensity of optical imaging in the visual cortex and the imaging signal reversibly disappears at 25 °C. Hyperthermia (39–41 °C) increases...
We present a new technique for acquiring and analyzing intrinsic signal optical images of brain activity, using continuous stimulus presentation and data acquisition. The main idea is to present a temporally periodic stimulus and to analyze the component of the response at the stimulus frequency. Advantages of the new technique include the removal of heart, respiration, and vasomotor artifacts, a...
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