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Fibulin-5 is a novel extracellular protein that is thought to act as a bridging peptide between elastin fibers and cell surface integrins in blood vessel wall. Fibulin-5 binding to endothelial cell (EC) surface integrins may effect cell proliferation and cell attachment to extracellular matrix (ECM) or to artificial surfaces. In this paper, we describe the effects of fibulin-5 on attachment, adhesion,...
Background: Pts with coronary disease and diabetes mellitus (DM) treated by balloon angioplasty (PTCA) were reported to have poorer 5 yr outcome than those treated by bypass surgery (CABG). We examined single center 12 yr survival in pt cohorts with multivessel disease with and without DM treated by PTCA or CABG in 1984-6.Methods: 95 consecutive pts had =< 1 vessel PTCA and 177 similar pts CABG,...
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