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Background: Patients with chronic cardiac failure (CCF) have abnormal vascular responses. Bradykinin (BK) is thought to contribute to the vasodilator effects of ACE inhibitors, but the effect of BK itself in patients with CCF has not been examined. Methods: We studied the responses to infused BK at 10, 30 and 100 pmol min -1 in patients with CCF (n=10) and controls (n=10). The slope of...
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