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Stimulus discrimination is the capacity of an organism to differentiate between stimuli and emit associated responses. The administration of the muscarinic antagonist scopolamine can be used as a stimulus by mammals in a discrimination task. The present study analyzes the contribution of the hippocampus in scopolamine discrimination and generalization. Male Wistar rats, weighing 250–300 g at the beginning...
Generation of plateau potentials in spinal motoneurons depends on activation of voltage sensitive L-type Ca 2+ channels. These channels are facilitated by metabotropic receptors known to promote release of Ca 2+ from intracellular stores. The aim of this study is to determine if Ca 2+ -release receptors in the endoplasmic reticulum (ER) that are sensitive to...
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