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ARS identical alleles are considered high resolution matched for unrelated donor stem cell transplant; however, it is unknown if mismatches outside of the ARS region impact transplant outcome. We investigated ARS identical allele pairs, HLA-A∗02:01/09, HLA-B∗44:02/27, HLA-C∗07:01/06 and C∗07:01/18, to determine if these alleles exist on the same haplotype in the Be the Match Registry®. The goal was...
The unselected sera from 869 human leucocyte antigen (HLA) immunized patients awaiting a kidney transplant were analysed using the complement-dependent lymphocytotoxicity test (LCT) with peripheral mononuclear blood cells and the complement-independent immune phagocytosis inhibition test (IPI) with monocytes derived from between five and 10 donors. Sera from 659 patients were LCT and IPI negative...
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