Search results for: Yan-li Zhao

Items from 1 to 20 out of 71 results

article

A safety and efficacy study of allogeneic haematopoietic stem cell transplantation for refractory and relapsed T‐cell acute lymphoblastic leukaemia/lymphoblastic lymphoma patients who achieved complete remission after autologous CD7 chimeric antigen receptor T‐cell therapy

Xing‐yu Cao, Jian‐ping Zhang, Yue Lu, Yan‐li Zhao, more

British Journal of Haematology > 204 > 6 > 2351 - 2364

CD7‐targeted chimeric antigen receptor T‐cell (CAR‐T) therapy has shown promising initial complete remission (CR) rates in patients with refractory or relapsed (r/r) T‐cell acute lymphoblastic leukaemia and lymphoblastic lymphoma (T‐ALL/LBL). To enhance the remission duration, consolidation with allogeneic haematopoietic stem cell transplantation (allo‐HSCT) is considered. Our study delved into the...

article

Analysis of 60 patients with relapsed or refractory T‐cell acute lymphoblastic leukemia and T‐cell lymphoblastic lymphoma treated with CD7‐targeted chimeric antigen receptor‐T cell therapy

Xian Zhang, Junfang Yang, Jingjing Li, Liyuan Qiu, more

American Journal of Hematology > 98 > 12 > 1898 - 1908

While the use of chimeric antigen receptor‐T (CAR‐T) therapy for T‐cell malignancies is in the early stage of clinical trials, it exhibits substantial potential to offer long‐term remission for patients with refractory/relapsed (R/R) T‐cell malignancies. In our phase I/II clinical trials, 65 pediatric and adult patients with R/R T‐cell acute lymphoblastic leukemia and lymphoblastic lymphoma (T‐ALL/LBL)...

article

The lived experiences of parents providing care to young people who self‐harm: A meta‐aggregative synthesis of qualitative studies

Yan‐li Zhao, Zhi‐hua Liu, Ying‐ying Li, Dong‐ling Liu, more

International Journal of Mental Health Nursing > 32 > 2 > 402 - 419

Self‐harm, which affects the whole family system, is an international public health concern. Empirical evidence supports the efficacy of interventions incorporating a family/parent training component for self‐injurious thoughts and behaviours, and a quantitative synthesis of these empirical studies has been undertaken and updated. A qualitative synthesis of the experiences of parents whose child self‐harms...

article

Basiliximab for steroid‐refractory acute graft‐versus‐host disease: A real‐world analysis

Xiao‐Dong Mo, Shen‐Da Hong, Yan‐Li Zhao, Er‐Lie Jiang, more

American Journal of Hematology > 97 > 4 > 458 - 469

Steroid‐refractory (SR) acute graft‐versus‐host disease (aGVHD) is one of the leading causes of early mortality after allogeneic hematopoietic stem cell transplantation (allo‐HSCT). We investigated the efficacy, safety, prognostic factors, and optimal therapeutic protocol for SR‐aGVHD patients treated with basiliximab in a real‐world setting. Nine hundred and forty SR‐aGVHD patients were recruited...

article

Discrimination and evaluation Gentiana rigescens–Camellia sinensis with different planting year using Fourier transform infrared spectroscopy

Li-Ju Mi, Ji Zhang, Yan-Li Zhao, Zhi-Tian Zuo, more

Agroforestry Systems > 2019 > 93 > 3 > 1157-1166

Agroforestry system, as the most promising substitute plantation approach, has been widely regarded as a prominent strategy for mitigating the conflicts between rapid growing population and limited arable land resources. This paper aims to screen the optimal planting pattern for Gentiana rigescens base on the content of gentiopicroside, providing the scientific basis for sustainable supply and application...

article

P50 suppression deficits and psychopathology in Han Chinese patients with schizophrenia

Xiao Lin Zhu, Shu Ping Tan, Zhi Ren Wang, Jin Guo Zhang, more

Neuroscience Letters > 2017 > 653 > C > 346-350

Numerous studies have reported P50 gating deficits in schizophrenia, though with mixed results. Moreover, few studies have explored the association between P50 gating deficits and psychopathology in Chinese patients with schizophrenia. In the present study, we investigated the P50 auditory sensory gating patterns and their correlations with clinical symptoms in a large sample of Han Chinese patients...

article

Quantitative determination and evaluation of Paris polyphylla var. yunnanensis with different harvesting times using UPLC‐UV‐MS and FT‐IR spectroscopy in combination with partial least squares discriminant analysis

Yuan‐Gui Yang, Ji Zhang, Yan‐Li Zhao, Jin‐Yu Zhang, more

Biomedical Chromatography > 31 > 7 > n/a - n/a

A rapid method was developed and validated by ultra‐performance liquid chromatography–triple quadrupole mass spectroscopy with ultraviolet detection (UPLC‐UV‐MS) for simultaneous determination of paris saponin I, paris saponin II, paris saponin VI and paris saponin VII. Partial least squares discriminant analysis (PLS‐DA) based on UPLC and Fourier transform infrared (FT‐IR) spectroscopy was employed...

article

Morphological variability and allometric relationships of the herb Panax notoginseng in Yunnan, China

Ji Zhang, Yan-Li Zhao, Hang Jin, Jin-Yu Zhang, more

Acta Ecologica Sinica > 2017 > 37 > 2 > 65-69

A plant's morphology changes throughout its ontogeny. Investigating the allometric relationships between different morphological traits could provide useful information for cultivation of medicinal plants. Here we collected 698 individuals of Panax notoginseng for allometric analysis from seven populations cultivated in Yunnan, Southwest China. The slopes and intercepts of the allometric relationships...

article

Chemotaxonomic Studies of Nine Gentianaceae Species from Western China Based on Liquid Chromatography Tandem Mass Spectrometry and Fourier Transform Infrared Spectroscopy

Yu Pan, Ji Zhang, Yan‐Li Zhao, Yuan‐Zhong Wang, more

Phytochemical Analysis > 27 > 3-4 > 158 - 167

IntroductionGentianaceae species which widely occur all over the world are used as folk medicine and raw food material with bitter properties. Although comparative analysis on metabolites in several Gentianaceae species has been reported, metabolic similarities used for chemotaxonomic studies are not yet clear. ObjectiveTo systematically characterise the variations of holistic metabolome and characteristic...

article

Experimental and theoretical investigation of structures and relative reactivity of Pr@C74 and Pr@C74(C6H3Cl2)

Yan-li Zhao, Qin Zhou, Yong-fu Lian, Hai-tao Yu

Diamond and Related Materials > 2016 > 64 > C > 110-118

Pr@C₇₄(C₆H₃Cl₂), a novel dichlorophenyl-functionalized derivative of the Pr-containing monometallofullerene Pr@C₇₄, was successfully prepared and isolated. Its molecular structure was determined as Pr@D_3h(14246)-C₇₄(C₆H₃Cl₂) by a combined mass spectrometry (MS), UV–visible-near-infrared (UV–vis-NIR) absorption spectroscopy, and quantum-mechanics characterization. Using the computed theoretical data,...

article

Minimal Residual Disease by Flow Cytometry Pre-Conditioning has Significant Impact on Disease-Free Survival after Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia

Yue Lu, Tong Wu, Yan-Li Zhao, Xing -Yu Cao, more

Biology of Blood and Marrow Transplantation > 2016 > 22 > 3(S) > S33

article

The Outcomes of Haploidentical Blood and Marrow Transplantation in Acute Leukemia: A Single-Center Study of 439 Cases

Yan-Li Zhao, Tong Wu, Yue Lu, Xing -Yu Cao, more

Biology of Blood and Marrow Transplantation > 2016 > 22 > 3(S) > S77

article

Phytochemistry and Pharmacological Activities of the Genus Gentiana (Gentianaceae)

Yu Pan, Yan‐Li Zhao, Ji Zhang, Wan‐Yi Li, more

Chemistry & Biodiversity > 13 > 2 > 107 - 150

article

Investigation of chemical diversity in different parts and origins of ethnomedicine Gentiana rigescens Franch using targeted metabolite profiling and multivariate statistical analysis

Yu Pan, Ji Zhang, Tao Shen, Yan‐Li Zhao, more

Biomedical Chromatography > 30 > 2 > 232 - 240

Gentiana rigescens, an ethnomedicine, is widely cultivated in Yunnan province of China. Although a wide range of metabolites including iridoid glycosides, flavonoids and triterpenoids have been reported in this ethnomedicine, the data on accumulation and distribution of metabolites in certain parts are limited. In this study, targeted metabolic fingerprinting of iridoid glycosides based on liquid...

article

Evaluation and quantitative analysis of different growth periods of herb–arbor intercropping systems using HPLC and UV–vis methods coupled with chemometrics

Bo-wen Chu, Ji Zhang, Zhi-min Li, Yan-li Zhao, more

Journal of Natural Medicines > 2016 > 70 > 4 > 803-810

As a result of the pressure from population explosion, agricultural land resources require further protecting and rationally utilizing. Intercropping technique has been widely applied for agricultural production to save cultivated area, improve crop quality, and promote agriculture economy. In this study, we employed high-performance liquid chromatography (HPLC) and ultraviolet–visible spectroscopy...

article

Comparative metabolic fingerprinting of Gentiana rhodantha from different geographical origins using LC-UV-MS/MS and multivariate statistical analysis

Yu Pan, Ji Zhang, Tao Shen, Yan-Li Zhao, more

BMC Biochemistry > 2015 > 16 > 1 > 1-10

Backgrounds Gentiana rhodantha , a rich source of iridoids and polyphenols, is a traditional ethnomedicine widely used in China. Metabolic fingerprinting based on a LC-UV-MS/MS method was applied to explore the chemical markers for discrimination of G. rhodantha from different geographical origins. Results Targeted compounds were separated on a Shim-pack...

article

Investigation of metabolites accumulation in medical plant Gentiana rigescens during different growing stage using LC-MS/MS and FT-IR

Yu Pan, Ji Zhang, Yan-Li Zhao, Yuan-Zhong Wang, more

Botanical Studies > 2015 > 56 > 1 > 1-9

Background Gentiana rigescens, an important medicinal plant in China, has been widely cultivated in Yunnan province, China. Previous studies were focused on analysis and determination of the metabolites isolated from this species, the accumulation of these metabolites during growth period are not yet clear. In this study, samples for the experiments were obtained by tissue culture. FT-IR and LC-MS/MS...

article

Simultaneous determination of six index constituents and comparative analysis of four ethnomedicines from genus Gentiana using a UPLC‐UV‐MS method

Yu Pan, Tao Shen, Ji Zhang, Yan‐Li Zhao, more

Biomedical Chromatography > 29 > 1 > 87 - 96

Many species from genus Gentiana (Gentianaceae) have a long history of applications as folk medicines in the world. A simple rapid UPLC‐UV‐MS/MS method has been developed and validated for the simultaneous determination of six index constituents (gentiopicroside, swertiamarin, loganic acid, sweroside, mangiferin and ferulic acid) from the four ethnomedicines (G. rigescens Franch. ex Hemsl., G. rhodantha...

article

Smoking, MATRICS consensus cognitive battery and P50 sensory gating in a Han Chinese population

Shu-Ping Tan, Jie-Feng Cui, Feng-Mei Fan, Yan-Li Zhao, more

Drug and Alcohol Dependence > 2014 > 143 > Complete > 51-57

The effects of smoking on cognitive performance have long been studied, with mixed results. P50 sensory gating has been used as endophenotype for studying nicotinic systems genetics, and P50 gating deficits have been reported to be a sensitive biomarker for cognitive impairment in schizophrenia. This study examined the inter-relationship between P50 suppression, cognitive function, and smoking in...

article

A mini-review of chemical composition and nutritional value of edible wild-grown mushroom from China

Xue-Mei Wang, Ji Zhang, Li-Hua Wu, Yan-Li Zhao, more

Food Chemistry > 2014 > 151 > Complete > 279-285

In China, many species of edible wild-grown mushrooms are appreciated as food and also found use in traditional Chinese medicine. In this mini-review, for the first time, is summarized and discussed data available on chemical components of nutritional significance for wild-grown mushrooms collected from China. We aimed to update and discuss the latest data published on ash, fat, carbohydrates, fibre,...

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INFONA - science communication portal

Search results for: Yan-li Zhao

A safety and efficacy study of allogeneic haematopoietic stem cell transplantation for refractory and relapsed T‐cell acute lymphoblastic leukaemia/lymphoblastic lymphoma patients who achieved complete remission after autologous CD7 chimeric antigen receptor T‐cell therapy

Analysis of 60 patients with relapsed or refractory T‐cell acute lymphoblastic leukemia and T‐cell lymphoblastic lymphoma treated with CD7‐targeted chimeric antigen receptor‐T cell therapy

The lived experiences of parents providing care to young people who self‐harm: A meta‐aggregative synthesis of qualitative studies

Basiliximab for steroid‐refractory acute graft‐versus‐host disease: A real‐world analysis

Discrimination and evaluation Gentiana rigescens–Camellia sinensis with different planting year using Fourier transform infrared spectroscopy

P50 suppression deficits and psychopathology in Han Chinese patients with schizophrenia

Quantitative determination and evaluation of Paris polyphylla var. yunnanensis with different harvesting times using UPLC‐UV‐MS and FT‐IR spectroscopy in combination with partial least squares discriminant analysis

Morphological variability and allometric relationships of the herb Panax notoginseng in Yunnan, China

Chemotaxonomic Studies of Nine Gentianaceae Species from Western China Based on Liquid Chromatography Tandem Mass Spectrometry and Fourier Transform Infrared Spectroscopy

Experimental and theoretical investigation of structures and relative reactivity of Pr@C74 and Pr@C74(C6H3Cl2)

Minimal Residual Disease by Flow Cytometry Pre-Conditioning has Significant Impact on Disease-Free Survival after Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia

The Outcomes of Haploidentical Blood and Marrow Transplantation in Acute Leukemia: A Single-Center Study of 439 Cases

Phytochemistry and Pharmacological Activities of the Genus Gentiana (Gentianaceae)

Investigation of chemical diversity in different parts and origins of ethnomedicine Gentiana rigescens Franch using targeted metabolite profiling and multivariate statistical analysis

Evaluation and quantitative analysis of different growth periods of herb–arbor intercropping systems using HPLC and UV–vis methods coupled with chemometrics

Comparative metabolic fingerprinting of Gentiana rhodantha from different geographical origins using LC-UV-MS/MS and multivariate statistical analysis

Investigation of metabolites accumulation in medical plant Gentiana rigescens during different growing stage using LC-MS/MS and FT-IR

Simultaneous determination of six index constituents and comparative analysis of four ethnomedicines from genus Gentiana using a UPLC‐UV‐MS method

Smoking, MATRICS consensus cognitive battery and P50 sensory gating in a Han Chinese population

A mini-review of chemical composition and nutritional value of edible wild-grown mushroom from China

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