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We present a wide field microscopy technique for the 3D mapping of optical intensity using Brownian gold nanoparticles as local probes. Localization by off-axis holography allows stochastic subwavelength optical characterization in water-based systems.
Cell movement has essential functions in development, immunity, and cancer. Various cell migration patterns have been reported, but no general rule has emerged so far. Here, we show on the basis of experimental data in vitro and in vivo that cell persistence, which quantifies the straightness of trajectories, is robustly coupled to cell migration speed. We suggest that this universal coupling constitutes...
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