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The human gene encoding the transcription factor C/EBPα was isolated from an umbilical cord genomic library screened by low stringency hybridization. Two overlapping clones were characterized by restriction enzyme analysis and included 13.2 kb of the C/EBPα locus. The entire gene and 471 bp of the promoter were sequenced. The human C/EBPα gene is 2783 bp long and encodes a 356 amino acid long protein,...