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Pediatric multiple sclerosis (MS) has long been an under-recognized MS subgroup. Fortunately, the special diagnostic challenges, the clinical course, treatment, and special needs of this MS subgroup are receiving increased attention. Pediatric MS occurs in most of the world although the frequency varies. Differential diagnoses such as the distinction from acute disseminated encephalomyelitis (ADEM)...
Diffusion tensor imaging (DTI) is a sensitive tool for detecting microstructural tissue damage in vivo. In this study, we investigated DTI abnormalities in individuals with relapsing remitting multiple sclerosis (RRMS) and examined the relations between imaging-based measures of white matter injury and cognitive impairment. DTI-derived metrics using tract-based spatial statistics (TBSS) were compared...
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