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The diffusion capacity for nitric oxide (DLNO) is independent of pulmonary capillary blood volume and equals the membrane diffusing capacity. Therefore the DLNO could be more sensitive in detecting alveolar destruction than the DLCO.We measured flow-volumes curves, DLNO, DLCO, the transfer coefficients KNO (DLNO/VA) and KCO (DLCO/VA) and performed computed tomography (CT) scans in 263 randomly selected...
A scheme for the automatic detection of nodules in thoracic computed tomography scans is presented and extensively evaluated. The algorithm uses the local image features of shape index and curvedness in order to detect candidate structures in the lung volume and applies two successive k-nearest-neighbour classifiers in the reduction of false-positives.The nodule detection system is trained and tested...
A new computer algorithm is presented to distinguish a special, most probably benign, subclass of lung nodules called perifissural opacities (PFO's), from potentially malignant nodules. The method focuses on the quantification of two characteristic properties of PFO's, namely the typical flattened surface of the nodule and its attachment to plate-like structures in the direct neighborhood of the nodule...
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