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The spontaneous mutant frequency in germ cells isolated from seminiferous tubules of two lambda/lacl transgenic mouse strains, C57BL/6 and B6C3F 1 was evaluated. At least 500 000 phage were screened for mutation at lacl for each animal using standardized assay procedures. The germ cell spontaneous lacl mutant frequency was 17.8±8.1 10 -6 in C57BL/6 mice and 17.0±10.0 10 ...
The spontaneous mutant frequency in germ cells isolated from seminiferous tubules of two lambda/lacI transgenic mouse strains, C57BL/6 and B6C3F 1 was evaluated. At least 500 000 phage were screened for mutation at lacI for each animal using standardized assay procedures. The germ cell spontaneous lacI mutant frequency was 17.8 ± 8.1 10 -6 in C57BL/6 mice and 17.0 ± 10.0...
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