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Recent preliminary data suggest that vaccination with Alzheimer's Aβ might reduce senile plaque load and stabilize cognitive decline in human Alzheimer's disease. To examine the mechanisms and consequences of anti-Aβ-antibody formation in a species more closely related to humans, rhesus monkeys (Macaca mulatta) were vaccinated with aggregated Aβ 1-42 . Immunized monkeys developed...
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