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Apolipoprotein CIII (apoCIII) is involved in triglyceride metabolism. More specifically, desialylation of apoCIII results in the inhibition of triglyceride catabolism. We therefore hypothesized that glycosylation/sialylation of apoCIII correlates with the elevated triglyceride concentrations observed in cord blood of IUGR fetuses.Venous cord blood samples of 36 IUGR and 49 preterm and term born controls...
Intrauterine growth restriction (IUGR) is a multifactorial condition in that the fetus does not reach its genetically given growth potential. Besides its contribution to perinatal mortality, it is a risk factor for cardiovascular and metabolic diseases later in life. The diagnosis is based on antenatal sonography, which allows differentiating between IUGR and fetuses that are small by constitution...
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