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In this study, an HPLC-DAD method was developed and validated for the quantification of bioactive phenolics in herbal medicines containing Cynara scolymus (Globe artichoke), Maytenus ilicifolia Mart ex Reiss “Espinheira santa” and Ptychopetalum uncinatum “Marapuama”. The samples were lyophilized and 5.0g of solid were extracted with 30mL of methanol acidified with 100μL of concentrated HCl, under...