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Background Size-specific dose estimate is gaining increased acceptance as the preferred index of CT dose in children. However it was developed based on non-clinical data. Objective To compare the accuracy of size-specific dose estimate (SSDE) based on geometric and body weight measures in pediatric chest and abdomen CT scans, versus the more accurate SSDE ¯ $$ \overline{\mathrm{SSDE}}...
Identification of facial dysmorphology is essential for the diagnosis of fetal alcohol syndrome (FAS); however, most children with fetal alcohol spectrum disorders (FASD) do not meet the dysmorphology criterion. Additional objective indicators are needed to help identify the broader spectrum of children affected by prenatal alcohol exposure. Computed tomography (CT) was used in a sheep model of prenatal...
Craniofacial bone dysmorphology is an important but under-explored potential diagnostic feature of fetal alcohol spectrum disorders. This study used longitudinal MicroCT 3D imaging to examine the effect of prenatal alcohol exposure on craniofacial bone growth in a mouse model. C57BL/6J dams were divided into 3 groups: alcohol 4.2% v/v in PMI ® liquid diet (ALC), 2 weeks prior to and during...
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