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The [ 14 C]-2-deoxyglucose (2-DG) technique was used to assess the rates of local cerebral glucose utilization (LCGU) in key limbic, cerebral cortical, hippocampal, basal ganglionic, and subcortical regions of alcohol-preferring (P) rats following chronic 24-h free-choice ethanol drinking. Adult male P rats were submitted to (1) 8 continuous weeks of two-bottle access to 15% ethanol and water...
The objective of the present study was to use quantitative autoradiography to determine binding densities of serotonin 1A (5-HT 1A ) and dopamine (DA) D 2 receptors in alcohol-naive periadolescent P and NP rat pups. P (n=8) and NP (n=7) rat pups, 25 days of age, from different litters were used. Coronal brain sections were incubated with 2 nM [ 3 H]8-OH-DPAT...
The densities of delta-opioid receptors in the central nervous system of alcohol-naive, adult, male, alcohol-preferring P, alcohol-nonpreferring NP, and Wistar rats were examined with the use of quantitative autoradiography. Slides with coronal 20-μm sections through the regions of interest were incubated in 5 nM [ 3 H]-[D-Pen 2 ,D-Pen 5 ]enkephalin (DPDPE) to label delta ...
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