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The results of a number of probabilistic safety assessments for German NPPs are presented which have shown the importance of common cause failures for the overall safety level of the plant. Binomial failure rate models and a process oriented simulation model for estimating CFF frequencies are described and their relative merits discussed.
Our hypothesis is that nitrogen loss in septic neonates is caused by increased muscle proteolysis. Sprague–Dawley rat pups (P7) were injected intraperitoneally with NaCl or 4 mg/kg/BW lipopolysaccharide (LPS) and then sacrificed at 2, 4, 24, and 48 hr. Sepsis syndrome was confirmed by elevated serum tumor necrosis factor (24.6 ng/mL ± 18.4 [LPS] and <1.0 ng/mL [controls]; p < .05). Proteolysis...
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