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Th accurate rapid, simple and selective reversed phase high performance liquid chromatography (RPHPLC) has been established and validated for the determination of captopril (CAP). Chromatographic separation was accomplished using prepacked ODSI C18 column (250 mm 3 4.6 mm with 5 mm particle size) in isocratic mode, with mobile phase consisting of water: acetonitrile (60:40 v/v), pH adjusted to 2.5...