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INTRODUCTION: Accumulating body of research has shown a cardinal bias for preference of spatially oriented targets in different species including humans, indicating greater neuronal responses in the primary visual cortex for horizontal or vertical contours in opposite to oblique ones. AIM(S): We used intrinsic signal optical imaging, a popular tool to map cortical function in rodents to verify the...
INTRODUCTION: It is accepted that learning induces plastic changes in adult neocortex. Our previous experiments on mice showed that classical conditioning in which monocular visual stimulation was paired with an electric shock to the tail enhanced GABA immunoreactivity within layer 4 of the monocular part of the primary visual cortex (V1), contralateral to the stimulated eye. AIM(S): In the present...
BACKGROUND AND AIMS: Previous study showed that associative pairing involving monocular visual stimulation resulted in a significant increase of the density of cells expressing glutamic acid decarboxylase (GAD), γ-aminobutyric acid (GABA) synthesizing enzyme, in mouse primary visual cortex contralateral to the stimulated eye. The effect was attributed to the group of parvalbumin- (PV)-negative interneurons,...
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