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The aim of this study was to evaluate the potential diagnostic usefulness of the full-length recombinant Toxoplasma gondii MAG1 protein by determining the levels of specific IgM and IgG antibodies in mouse and human sera obtained from individuals with acute and chronic toxoplasmosis. The obtained results revealed that IgG antibodies against MAG1 are a sensitive and specific marker of T. gondii infection...
Taking into account the literature reports on the involvement of prolactin (PRL) in the regulation of immunity against Toxoplasma gondii, we decided to check whether this parasite has the ability to bind the lactotrophic hormone. We examined T. gondii binding of sheep fluoresceine- and biotine-labeled prolactin isolated from pituitary (shPRL). In this work we announced for the first time that shPRL...
The parasitic protozoan Toxoplasma gondii is capable of altering intermediate host natural defensive behavior, which is believed to facilitate the parasite’s transmission in the environment. Despite extensive research on the subject, the exact mechanism behind the host manipulation remains obscure. However, key neurotransmitter levels are listed among possible contributing factors. Thus, the study...
Despite many years of studies on the mechanisms of immunological defence responses induced in host organisms by Toxoplasma, no satisfactory immunoprophylaxis or chemotherapy have yet been established for humans. Thus, alternative methods to prevent toxoplasmosis and to enhance the efficacy of currently used antitoxoplasmic drugs are under evaluation. In this work, we strove to determine the influence...
Macrophage-mediated early nonspecific immunological response is an important part of the immunity against intracellular parasite Toxoplasma gondii. The immunological functions of macrophages are closely connected with iron metabolism and acquiring of iron mainly from transferrin by the receptor-mediated endocytosis. The level of specific transferrin receptors can be modulated by different soluble...
Анализировали величину и причины потерь поросят от первородящих и многородящих свиноматок пород крупной белой польской и дюрок до 70-дневного возраста. Исследовательский материал составляли данные касающиеся 1147 павших поросят в период 1985 и 1986 гг. в Гибриднзационном центре Павловице. Число мертворожденных поросят было выше в пометах свиноматок породы дюрок. В период откармливания до 21-го дня...
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