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Increased ROS generation by the overload by metabolic substrates mitochondria paralleled by decrease of antioxidant activity are typical events found in metabolic syndrome and diabetes type 2. Metabolites of beta-carotene (BC) such as retinoic acid (RA), as well as low concentration of reactive oxygen species (ROS) modify the mitochondrial bioenergetic function. The aim of the study was to investigate...
CCL3 and CCL4 are proinflammatory chemokines belonging to the CC family. Increase in expression of mRNA coding for various chemokines including CCL3 and CCL4 has been often detected with global transcriptome profiling of brain tissue following epileptogenic stimuli as well as in epilepsy in experimental models and in human patients. Despite this, little is known about the expression of these proteins...
MBD3 is a member of the family of methyl-CpG binding domain containing proteins. It is a component of a multisubunit complex involved in nucleosome remodeling and histone deacetylation. MBD3 does not bind to DNA, but recruits histone deacetylases and DNA methyltransefases and can act as transcriptional repressor. The aim of this study was to verify if MBD3 is involved in epigenetic mechanisms leading...
Investigated were changes in selected redox parameters – vitamin C, malondialdehyde (MDA) and glutathione (GSH) content of goat blood plasma – as markers of oxidative stress after per os administration the N-acetylcysteine (NAC). Used were 20 Polish White Improved goats, selected from the flock of 60 animals. Within the selected goats distinguished were four groups according to somatic cell counts...
Twenty males were used from generation 8 of rabbits divergently selected for high (line H, n=10) vs. low (line L, n=10) locomotor activity in the open-field (OF-test). At the age of 98 days, blond samples were withdrawn from the ear vein and the rabbits were killed. Immediately, liver, kidney and the left femoral muscle samples were excised. In lysosomal fractions of blood serum and three tissues...
During a 6-year field study on the game farm ‘Benfontein’ in the central Republic of South Africa 1725 prey items were observed consumed by 17 free-ranging habituated black-footed catsFelis nigripes Burchell, 1824. Average prey size was 24.1 g. Eight males fed on significantly larger prey (27.9 g) than 9 females (20.8 g). Fifty-four prey species were classified by their average mass into 8 different...
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